Manufacturer
Brand Dragon Pharma
Last Lab Tested None
Core Information
Substance CJC-1295 with DAC
Classification Growth Hormone Releasing Hormone (GHRH) analog
Active Half-Life 6–8 days
Typical Dosage (Men) 1–2 mg/week (1–2 injections weekly)
Effects & Properties
Water Retention Moderate
Aromatization No
Hepatotoxicity No
Hair Loss Risk (HBR) No
Acne Low–Moderate
What Is CJC-1295 DAC?
Dragon Pharma CJC-1295 DAC is a long-acting growth hormone secretagogue designed for advanced peptide research. As a synthetic GHRH analog, it mimics the first 29 amino acids of endogenous growth hormone-releasing hormone while incorporating four molecular stabilizations that resist enzymatic breakdown.
The Drug Affinity Complex (DAC) differentiates this formula from standard GRF 1-29. By binding reversibly to serum albumin, the DAC modification extends the circulating half-life to approximately eight days. This creates a sustained elevation in growth hormone and IGF-1 output without the frequent dosing demands of short-acting alternatives.
How Does CJC-1295 DAC Work?
This peptide initiates signaling through the GHRH receptor on pituitary somatotroph cells. Activation triggers the G-protein coupled cascade, increasing cyclic AMP and activating protein kinases that upregulate growth hormone gene transcription.
Released growth hormone travels to hepatic tissue, stimulating IGF-1 synthesis via the JAK-STAT pathway. Unlike direct HGH administration, this GHRH analog preserves the body's natural pulsatile secretion rhythm while amplifying both peak amplitude and baseline levels.
Key Benefits
- Sustained GH Elevation: Research models indicate up to 7.5-fold increases in peak growth hormone concentration from a single exposure.
- Prolonged IGF-1 Release: Elevated insulin-like growth factor 1 levels persist for 9–11 days, with cumulative effects observed over 28 days.
- Reduced Injection Frequency: The albumin-binding DAC component allows for weekly or bi-weekly administration in laboratory settings.
- Physiological Pulsatility: Maintains natural high-low expression patterns rather than overriding endocrine feedback loops.
- Cellular Proliferation Support: Studies suggest increased pituitary RNA and GH mRNA, indicating potential somatotroph cell proliferation.
- Body Composition Research: Murine data implies favorable shifts in lean mass relative to adipose tissue in growth hormone deficient models.
Why Researchers Choose Dragon Pharma CJC-1295 DAC
When investigating growth hormone physiology, peptide stability and dosing accuracy determine data integrity. This long-acting GHRH analog combines verified molecular structure with extended pharmacokinetics, reducing experimental variability while maximizing endocrine stimulation.
From pituitary cell studies to metabolic research, Dragon Pharma delivers the consistency required for reproducible scientific outcomes. Buy CJC-1295 DAC online from a trusted source and ensure your laboratory work meets the highest standards of precision.